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The 3D structure of Kaposi sarcoma herpesvirus LANA C-terminal domain bound to DNA

Kaposi sarcoma herpesvirus (KSHV) persists as a latent nuclear episome in dividing host cells. This episome is tethered to host chromatin to ensure proper segregation during mitosis. For duplication of the latent genome, the cellular replication machinery is recruited. Both of these functions rely o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Hellert, Jan, Weidner-Glunde, Magdalena, Krausze, Joern, Lünsdorf, Heinrich, Ritter, Christiane, Schulz, Thomas F., Lührs, Thorsten
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450395/
https://ncbi.nlm.nih.gov/pubmed/25947153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421804112
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