The 3D structure of Kaposi sarcoma herpesvirus LANA C-terminal domain bound to DNA

Kaposi sarcoma herpesvirus (KSHV) persists as a latent nuclear episome in dividing host cells. This episome is tethered to host chromatin to ensure proper segregation during mitosis. For duplication of the latent genome, the cellular replication machinery is recruited. Both of these functions rely o...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Hellert, Jan, Weidner-Glunde, Magdalena, Krausze, Joern, Lünsdorf, Heinrich, Ritter, Christiane, Schulz, Thomas F., Lührs, Thorsten
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450395/
https://ncbi.nlm.nih.gov/pubmed/25947153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421804112
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