The 3D structure of Kaposi sarcoma herpesvirus LANA C-terminal domain bound to DNA

Kaposi sarcoma herpesvirus (KSHV) persists as a latent nuclear episome in dividing host cells. This episome is tethered to host chromatin to ensure proper segregation during mitosis. For duplication of the latent genome, the cellular replication machinery is recruited. Both of these functions rely o...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Hellert, Jan, Weidner-Glunde, Magdalena, Krausze, Joern, Lünsdorf, Heinrich, Ritter, Christiane, Schulz, Thomas F., Lührs, Thorsten
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450395/
https://ncbi.nlm.nih.gov/pubmed/25947153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421804112
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