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The 3D structure of Kaposi sarcoma herpesvirus LANA C-terminal domain bound to DNA

Kaposi sarcoma herpesvirus (KSHV) persists as a latent nuclear episome in dividing host cells. This episome is tethered to host chromatin to ensure proper segregation during mitosis. For duplication of the latent genome, the cellular replication machinery is recruited. Both of these functions rely o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hellert, Jan, Weidner-Glunde, Magdalena, Krausze, Joern, Lünsdorf, Heinrich, Ritter, Christiane, Schulz, Thomas F., Lührs, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450395/
https://ncbi.nlm.nih.gov/pubmed/25947153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421804112
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