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Crystallization, room-temperature X-ray diffraction and preliminary analysis of Kaposi’s sarcoma herpesvirus LANA bound to DNA

The latency-associated nuclear antigen (LANA) is the latent origin-binding protein and chromatin anchor of the Kaposi’s sarcoma herpesvirus (KSHV/HHV-8) genome. Its C-terminal domain (CTD) binds sequence-specifically to the viral origin of replication, whereas the N-terminal domain links it to nucle...

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Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Hellert, Jan, Krausze, Joern, Schulz, Thomas F., Lührs, Thorsten
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231869/
https://ncbi.nlm.nih.gov/pubmed/25372834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14019906
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