Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS

The latency-associated nuclear antigen (LANA) of Kaposi sarcoma herpesvirus (KSHV) is mainly localized and functions in the nucleus of latently infected cells, playing a pivotal role in the replication and maintenance of latent viral episomal DNA. In addition, N-terminally truncated cytoplasmic isof...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Zhang, Guigen, Chan, Baca, Samarina, Naira, Abere, Bizunesh, Weidner-Glunde, Magdalena, Buch, Anna, Pich, Andreas, Brinkmann, Melanie M., Schulz, Thomas F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776510/
https://ncbi.nlm.nih.gov/pubmed/26811480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516812113
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