Inhibiting the Recruitment of PLCγ1 to Kaposi’s Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells

Kaposi’s sarcoma (KS), caused by Kaposi’s sarcoma herpesvirus (KSHV), is a highly vascularised tumour of endothelial origin. KSHV infected endothelial cells show increased invasiveness and angiogenesis. Here, we report that the KSHV K15 protein, which we showed previously to contribute to KSHV-induc...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Gramolelli, Silvia, Weidner-Glunde, Magdalena, Abere, Bizunesh, Viejo-Borbolla, Abel, Bala, Kiran, Rückert, Jessica, Kremmer, Elisabeth, Schulz, Thomas F.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546648/
https://ncbi.nlm.nih.gov/pubmed/26295810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005105
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