Inhibiting the Recruitment of PLCγ1 to Kaposi’s Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells

Kaposi’s sarcoma (KS), caused by Kaposi’s sarcoma herpesvirus (KSHV), is a highly vascularised tumour of endothelial origin. KSHV infected endothelial cells show increased invasiveness and angiogenesis. Here, we report that the KSHV K15 protein, which we showed previously to contribute to KSHV-induc...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Gramolelli, Silvia, Weidner-Glunde, Magdalena, Abere, Bizunesh, Viejo-Borbolla, Abel, Bala, Kiran, Rückert, Jessica, Kremmer, Elisabeth, Schulz, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546648/
https://ncbi.nlm.nih.gov/pubmed/26295810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005105
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