Kaposi's Sarcoma-Associated Herpesvirus Nonstructural Membrane Protein pK15 Recruits the Class II Phosphatidylinositol 3-Kinase PI3K-C2α To Activate Productive Viral Replication

Kaposi's sarcoma (KS)-associated herpesvirus (KSHV)/human herpesvirus 8 (HHV-8) causes the angiogenic tumor KS and two B-cell malignancies. The KSHV nonstructural membrane protein encoded by the open reading frame (ORF) K15 recruits and activates several cellular proteins, including phospholipa...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Abere, Bizunesh, Samarina, Naira, Gramolelli, Silvia, Rückert, Jessica, Gerold, Gisa, Pich, Andreas, Schulz, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096797/
https://ncbi.nlm.nih.gov/pubmed/29950425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00544-18
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