Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation

Kaposi Sarcoma-associated herpesvirus (KSHV) causes three human malignancies, Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and the plasma cell variant of multicentric Castleman’s Disease (MCD), as well as an inflammatory cytokine syndrome (KICS). Its non-structural membrane protein, pK15, is...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Samarina, Naira, Ssebyatika, George, Tikla, Tanvi, Waldmann, Ja-Yun, Abere, Bizunesh, Nanna, Vittoria, Marasco, Michelangelo, Carlomagno, Teresa, Krey, Thomas, Schulz, Thomas F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244865/
https://ncbi.nlm.nih.gov/pubmed/34143834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009635
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