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Site-Specific Cryo-focused Ion Beam Sample Preparation Guided by 3D Correlative Microscopy
The development of cryo-focused ion beam (cryo-FIB) for the thinning of frozen-hydrated biological specimens enabled cryo-electron tomography (cryo-ET) analysis in unperturbed cells and tissues. However, the volume represented within a typical FIB lamella constitutes a small fraction of the biologic...
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| Veröffentlicht in: | Biophys J |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4775854/ https://ncbi.nlm.nih.gov/pubmed/26769364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.053 |
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