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Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase

The importance of protonation states and proton transfer in pyridoxal 5′-phosphate (PLP)-chemistry can hardly be overstated. Although experimental approaches to investigate pKa values can provide general guidance for assigning proton locations, only static pictures of the chemical species are availa...

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Bibliografiske detaljer
Udgivet i:J Mol Recognit
Main Authors: Huang, Yu-ming M., You, Wanli, Caulkins, Bethany G., Dunn, Michael F., Mueller, Leonard J., Chang, Chia-en A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774508/
https://ncbi.nlm.nih.gov/pubmed/25042708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.2377
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