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Protonation states and catalysis: Molecular dynamics studies of intermediates in tryptophan synthase
The importance of protonation states and proton transfer in pyridoxal 5′-phosphate (PLP)-chemistry can hardly be overstated. Although experimental approaches to investigate pKa values can provide general guidance for assigning proton locations, only static pictures of the chemical species are availa...
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| Vydáno v: | J Mol Recognit |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4774508/ https://ncbi.nlm.nih.gov/pubmed/25042708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.2377 |
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