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Development of a Rapid Throughput Assay for Identification of hNa(v)1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin
Voltage-gated sodium channels (VGSCs) are responsible for the generation of the action potential. Among nine classified VGSC subtypes (Na(v)1.1–Na(v)1.9), Na(v)1.7 is primarily expressed in the sensory neurons, contributing to the nociception transmission. Therefore Na(v)1.7 becomes a promising targ...
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| 出版年: | Mar Drugs |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4771989/ https://ncbi.nlm.nih.gov/pubmed/26891306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14020036 |
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