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Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation

Osteoblast-mediated bone formation is coupled to osteoclast-mediated bone resorption. These processes become uncoupled with age, leading to increased risk for debilitating fractures. Therefore, understanding how osteoblasts are recruited to sites of resorption is vital to treating age-related bone l...

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Détails bibliographiques
Publié dans:J Bone Miner Res
Auteurs principaux: Weivoda, Megan M, Ruan, Ming, Pederson, Larry, Hachfeld, Christine, Davey, Rachel A, Zajac, Jeffrey D, Westendorf, Jennifer J, Khosla, Sundeep, Oursler, Merry Jo
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758668/
https://ncbi.nlm.nih.gov/pubmed/26108893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2586
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