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Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

Under most conditions, resorbed bone is nearly precisely replaced in location and amount by new bone. Thus, it has long been recognized that bone loss through osteoclast-mediated bone resorption and bone replacement through osteoblast-mediated bone formation are tightly coupled processes. Abundant d...

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Autori principali: Pederson, Larry, Ruan, Ming, Westendorf, Jennifer J., Khosla, Sundeep, Oursler, Merry Jo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603259/
https://ncbi.nlm.nih.gov/pubmed/19075223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805133106
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