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Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation

Osteoblast-mediated bone formation is coupled to osteoclast-mediated bone resorption. These processes become uncoupled with age, leading to increased risk for debilitating fractures. Therefore, understanding how osteoblasts are recruited to sites of resorption is vital to treating age-related bone l...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Weivoda, Megan M, Ruan, Ming, Pederson, Larry, Hachfeld, Christine, Davey, Rachel A, Zajac, Jeffrey D, Westendorf, Jennifer J, Khosla, Sundeep, Oursler, Merry Jo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758668/
https://ncbi.nlm.nih.gov/pubmed/26108893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2586
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