Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation

Osteoblast-mediated bone formation is coupled to osteoclast-mediated bone resorption. These processes become uncoupled with age, leading to increased risk for debilitating fractures. Therefore, understanding how osteoblasts are recruited to sites of resorption is vital to treating age-related bone l...

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Vydáno v:J Bone Miner Res
Hlavní autoři: Weivoda, Megan M, Ruan, Ming, Pederson, Larry, Hachfeld, Christine, Davey, Rachel A, Zajac, Jeffrey D, Westendorf, Jennifer J, Khosla, Sundeep, Oursler, Merry Jo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758668/
https://ncbi.nlm.nih.gov/pubmed/26108893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2586
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