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Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation

Osteoblast-mediated bone formation is coupled to osteoclast-mediated bone resorption. These processes become uncoupled with age, leading to increased risk for debilitating fractures. Therefore, understanding how osteoblasts are recruited to sites of resorption is vital to treating age-related bone l...

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Bibliografske podrobnosti
izdano v:J Bone Miner Res
Main Authors: Weivoda, Megan M, Ruan, Ming, Pederson, Larry, Hachfeld, Christine, Davey, Rachel A, Zajac, Jeffrey D, Westendorf, Jennifer J, Khosla, Sundeep, Oursler, Merry Jo
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758668/
https://ncbi.nlm.nih.gov/pubmed/26108893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2586
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