Osteoclast TGF-β Receptor Signaling Induces Wnt1 Secretion and Couples Bone Resorption to Bone Formation

Osteoblast-mediated bone formation is coupled to osteoclast-mediated bone resorption. These processes become uncoupled with age, leading to increased risk for debilitating fractures. Therefore, understanding how osteoblasts are recruited to sites of resorption is vital to treating age-related bone l...

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Bibliografische gegevens
Gepubliceerd in:J Bone Miner Res
Hoofdauteurs: Weivoda, Megan M, Ruan, Ming, Pederson, Larry, Hachfeld, Christine, Davey, Rachel A, Zajac, Jeffrey D, Westendorf, Jennifer J, Khosla, Sundeep, Oursler, Merry Jo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758668/
https://ncbi.nlm.nih.gov/pubmed/26108893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2586
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