Sclerostin Is Expressed in Osteoclasts From Aged Mice and Reduces Osteoclast-Mediated Stimulation of Mineralization

Osteoclast-mediated bone resorption precedes osteoblast-mediated bone formation through early adulthood, but formation fails to keep pace with resorption during aging. We previously identified several factors produced by osteoclasts that promote bone formation. In this study, we determined if osteoc...

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Bibliographic Details
Main Authors: Ota, Kuniaki, Quint, Patrick, Ruan, Ming, Pederson, Larry, Westendorf, Jennifer J., Khosla, Sundeep, Oursler, Merry Jo
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895454/
https://ncbi.nlm.nih.gov/pubmed/23494985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24537
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