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Sclerostin Is Expressed in Osteoclasts From Aged Mice and Reduces Osteoclast-Mediated Stimulation of Mineralization

Osteoclast-mediated bone resorption precedes osteoblast-mediated bone formation through early adulthood, but formation fails to keep pace with resorption during aging. We previously identified several factors produced by osteoclasts that promote bone formation. In this study, we determined if osteoc...

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Detalhes bibliográficos
Main Authors: Ota, Kuniaki, Quint, Patrick, Ruan, Ming, Pederson, Larry, Westendorf, Jennifer J., Khosla, Sundeep, Oursler, Merry Jo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895454/
https://ncbi.nlm.nih.gov/pubmed/23494985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24537
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