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Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3' regulatory region
The IgH 3' regulatory region (3'RR) controls class switch recombination (CSR) and somatic hypermutation (SHM) in B cells. The mouse 3'RR contains four enhancer elements with hs1,2 flanked by inverted repeated sequences and the centre of a 25-kb palindrome bounded by two hs3 enhancer i...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757795/ https://ncbi.nlm.nih.gov/pubmed/26883548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10730 |
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