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The immunoglobulin heavy chain 3′ regulatory region superenhancer controls mouse B1 B-cell fate and late VDJ repertoire diversity

The immunoglobulin heavy chain (IgH) 3′ regulatory region (3′RR) superenhancer controls B2 B-cell IgH transcription and cell fate at the mature stage but not early repertoire diversity. B1 B cells represent a small percentage of total B cells differing from B2 B cells by several points such as precu...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Ghazzaui, Nour, Issaoui, Hussein, Saintamand, Alexis, Oblet, Christelle, Carrion, Claire, Denizot, Yves
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812333/
https://ncbi.nlm.nih.gov/pubmed/29437640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017014423
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