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Targeting the oncogene B lymphoma deregulator IgH 3′ regulatory region does not impede the in vivo inflammatory response in mice

The IgH 3′ regulatory region (3′RR), encompassing the four transcriptional enhancers hs3a-hs1,2-hs3b-hs4, is a potent lymphoma oncogene deregulator but its role in B cell-mediated inflammatory responses is unknown. We investigated the 3′RR involvement in the in vivo pristane-induced inflammatory res...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Saad, Faten, Saintamand, Alexis, Rouaud, Pauline, Denizot, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278336/
https://ncbi.nlm.nih.gov/pubmed/25594069
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