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Mangrove dolabrane‐type of diterpenes tagalsins suppresses tumor growth via ROS‐mediated apoptosis and ATM/ATR–Chk1/Chk2‐regulated cell cycle arrest

Natural compounds are an important source for drug development. With an increasing cancer rate worldwide there is an urgent quest for new anti‐cancer drugs. In this study, we show that a group of dolabrane‐type of diterpenes, collectively named tagalsins, isolated from the Chinese mangrove genus Cer...

詳細記述

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書誌詳細
出版年:Int J Cancer
主要な著者: Neumann, Jennifer, Yang, Yi, Köhler, Rebecca, Giaisi, Marco, Witzens‐Harig, Mathias, Liu, Dong, Krammer, Peter H., Lin, Wenhan, Li‐Weber, Min
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755134/
https://ncbi.nlm.nih.gov/pubmed/26061604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29629
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