ATM‐CHK2‐Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress

The homeostatic link between oxidative stress and autophagy plays an important role in cellular responses to a wide variety of physiological and pathological conditions. However, the regulatory pathway and outcomes remain incompletely understood. Here, we show that reactive oxygen species (ROS) func...

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Pubblicato in:EMBO J
Autori principali: Guo, Qi‐Qiang, Wang, Shan‐Shan, Zhang, Shan‐Shan, Xu, Hong‐De, Li, Xiao‐Man, Guan, Yi, Yi, Fei, Zhou, Ting‐Ting, Jiang, Bo, Bai, Ning, Ma, Meng‐Tao, Wang, Zhuo, Feng, Yan‐Ling, Guo, Wen‐Dong, Wu, Xuan, Zhao, Gui‐Feng, Fan, Guang‐Jian, Zhang, Sheng‐Ping, Wang, Chuan‐Gui, Cao, Long‐Yue, O'Rourke, Brian P, Liu, Shi‐Hui, Wang, Ping‐Yuan, Han, Shuai, Song, Xiao‐Yu, Cao, Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232007/
https://ncbi.nlm.nih.gov/pubmed/32187724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103111
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