7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells

Cardiovascular diseases (atherosclerosis, stroke, myocardiac infarction etc.) are the major systemic diseases of elder peoples in the world. This is possibly due to increased levels of oxidized low-density lipoproteins (oxLDLs) such as 7-ketocholesterol (7-KC) and lysophosphatidylcholine (LPC) that...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chang, Mei-Chi, Chen, Yi-Jane, Liou, Eric Jein-Wein, Tseng, Wan-Yu, Chan, Chiu-Po, Lin, Hseuh-Jen, Liao, Wan-Chuen, Chang, Ya-Ching, Jeng, Po-Yuan, Jeng, Jiiang-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342680/
https://ncbi.nlm.nih.gov/pubmed/27740938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12578
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