7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells

Cardiovascular diseases (atherosclerosis, stroke, myocardiac infarction etc.) are the major systemic diseases of elder peoples in the world. This is possibly due to increased levels of oxidized low-density lipoproteins (oxLDLs) such as 7-ketocholesterol (7-KC) and lysophosphatidylcholine (LPC) that...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Chang, Mei-Chi, Chen, Yi-Jane, Liou, Eric Jein-Wein, Tseng, Wan-Yu, Chan, Chiu-Po, Lin, Hseuh-Jen, Liao, Wan-Chuen, Chang, Ya-Ching, Jeng, Po-Yuan, Jeng, Jiiang-Huei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper: Gerotarget (Focus on Aging)
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342680/
https://ncbi.nlm.nih.gov/pubmed/27740938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12578
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