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Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells

Repair of DNA double-strand breaks (DSBs) by non-homologous end-joining is critical for neural development, and brain cells frequently contain somatic genomic variations that might involve DSB intermediates. We now use an unbiased, high-throughput approach to identify genomic regions harboring recur...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Wei, Pei-Chi, Chang, Amelia N., Kao, Jennifer, Du, Zhou, Meyers, Robin M., Alt, Frederick W., Schwer, Bjoern
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752721/
https://ncbi.nlm.nih.gov/pubmed/26871630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.12.039
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