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Potent Multi-target FAAH-COX Inhibitors: Design and Structure-Activity Relationship Studies
Non-steroidal anti-inflammatory drugs (NSAIDs) exert their pharmacological effects by inhibiting cyclooxygenase (COX)-1 and COX-2. Though widely prescribed for pain and inflammation, these agents have limited utility in chronic diseases due to serious mechanism-based adverse events such as gastroint...
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| Gepubliceerd in: | Eur J Med Chem |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752335/ https://ncbi.nlm.nih.gov/pubmed/26774927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.12.036 |
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