Identification and characterization of carprofen as a multi-target FAAH/COX inhibitor

Pain and inflammation are major therapeutic areas for drug discovery. Current drugs for these pathologies have limited efficacy, however, and often cause a number of unwanted side effects. In the present study, we identify the non-steroid anti-inflammatory drug, carprofen, as a multi-target-directed...

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Main Authors: Favia, Angelo D., Habrant, Damien, Scarpelli, Rita, Migliore, Marco, Albani, Clara, Bertozzi, Sine Mandrup, Dionisi, Mauro, Tarozzo, Glauco, Piomelli, Daniele, Cavalli, Andrea, De Vivo, Marco
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764917/
https://ncbi.nlm.nih.gov/pubmed/23043222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3011146
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