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Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions

Fatty-acid amide hydrolase (FAAH) catalyzes the intracellular hydrolysis of the endocannabinoid anandamide and other bioactive lipid amides. In the present study, we conducted a comparative characterization of the effects of the newly identified brain-impermeant FAAH inhibitor, URB937 ([3-(3-carbamo...

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Autors principals: SASSO, Oscar, BERTORELLI, Rosalia, BANDIERA, Tiziano, SCARPELLI, Rita, COLOMBANO, Giampiero, ARMIROTTI, Andrea, MORENO-SANZ, Guillermo, REGGIANI, Angelo, PIOMELLI, Daniele
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738192/
https://ncbi.nlm.nih.gov/pubmed/22420940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2012.02.012
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