Potent Multi-target FAAH-COX Inhibitors: Design and Structure-Activity Relationship Studies

Non-steroidal anti-inflammatory drugs (NSAIDs) exert their pharmacological effects by inhibiting cyclooxygenase (COX)-1 and COX-2. Though widely prescribed for pain and inflammation, these agents have limited utility in chronic diseases due to serious mechanism-based adverse events such as gastroint...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Med Chem
Egile Nagusiak: Migliore, Marco, Habrant, Damien, Sasso, Oscar, Albani, Clara, Bertozzi, Sine Mandrup, Armirotti, Andrea, Piomelli, Daniele, Scarpelli, Rita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752335/
https://ncbi.nlm.nih.gov/pubmed/26774927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.12.036
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