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BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice
Precise regulation of transcription is crucial for the cellular mechanisms underlying memory formation. However, the link between neuronal stimulation and the proteins that directly interact with histone modifications to activate transcription in neurons remains unclear. Brd4 is a member of the BET...
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| Vydáno v: | Nat Neurosci |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752120/ https://ncbi.nlm.nih.gov/pubmed/26301327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4095 |
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