Загрузка...

BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice

Precise regulation of transcription is crucial for the cellular mechanisms underlying memory formation. However, the link between neuronal stimulation and the proteins that directly interact with histone modifications to activate transcription in neurons remains unclear. Brd4 is a member of the BET...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nat Neurosci
Главные авторы: Korb, Erica, Herre, Margo, Zucker-Scharff, Ilana, Darnell, Robert B., Allis, C. David
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752120/
https://ncbi.nlm.nih.gov/pubmed/26301327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4095
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!