BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice

Por Korb, Erica, Herre, Margo, Zucker-Scharff, Ilana, Darnell, Robert B., Allis, C. David
Publicado no Nat Neurosci (2015)

Excess translation of epigenetic regulators contributes to Fragile X Syndrome and is alleviated by Brd4 inhibition

Por Korb, Erica, Herre, Margaret, Zucker-Scharff, Ilana, Gresack, Jodi, Allis, C. David, Darnell, Robert B.
Publicado no Cell (2017)

cTag-PAPERCLIP reveals alternative polyadenylation promotes cell-type specific protein diversity and switches Araf isoforms with microglia activation

Por Hwang, Hun-Way, Saito, Yuhki, Park, Christopher Y., Blachère, Nathalie E., Tajima, Yoko, Fak, John J., Zucker-Scharff, Ilana, Darnell, Robert B.
Publicado no Neuron (2017)

ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity

Por Moore, Michael J, Blachere, Nathalie E, Fak, John J, Park, Christopher Y, Sawicka, Kirsty, Parveen, Salina, Zucker-Scharff, Ilana, Moltedo, Bruno, Rudensky, Alexander Y, Darnell, Robert B
Publicado no eLife (2018)

Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain

Por Scheckel, Claudia, Drapeau, Elodie, Frias, Maria A, Park, Christopher Y, Fak, John, Zucker-Scharff, Ilana, Kou, Yan, Haroutunian, Vahram, Ma'ayan, Avi, Buxbaum, Joseph D, Darnell, Robert B
Publicado no eLife (2016)

Dopamine neuron dependent behaviors mediated by glutamate cotransmission

Por Mingote, Susana, Chuhma, Nao, Kalmbach, Abigail, Thomsen, Gretchen M, Wang, Yvonne, Mihali, Andra, Sferrazza, Caroline, Zucker-Scharff, Ilana, Siena, Anna-Claire, Welch, Martha G, Lizardi-Ortiz, José, Sulzer, David, Moore, Holly, Gaisler-Salomon, Inna, Rayport, Stephen
Publicado no eLife (2017)

A majority of m(6)A residues are in the last exons, allowing the potential for 3′ UTR regulation

Por Ke, Shengdong, Alemu, Endalkachew A., Mertens, Claudia, Gantman, Emily Conn, Fak, John J., Mele, Aldo, Haripal, Bhagwattie, Zucker-Scharff, Ilana, Moore, Michael J., Park, Christopher Y., Vågbø, Cathrine Broberg, Kusśnierczyk, Anna, Klungland, Arne, Darnell, James E., Darnell, Robert B.
Publicado no Genes Dev (2015)