Dopamine neuron dependent behaviors mediated by glutamate cotransmission

Dopamine neurons in the ventral tegmental area use glutamate as a cotransmitter. To elucidate the behavioral role of the cotransmission, we targeted the glutamate-recycling enzyme glutaminase (gene Gls1). In mice with a dopamine transporter (Slc6a3)-driven conditional heterozygous (cHET) reduction o...

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Vydáno v:eLife
Hlavní autoři: Mingote, Susana, Chuhma, Nao, Kalmbach, Abigail, Thomsen, Gretchen M, Wang, Yvonne, Mihali, Andra, Sferrazza, Caroline, Zucker-Scharff, Ilana, Siena, Anna-Claire, Welch, Martha G, Lizardi-Ortiz, José, Sulzer, David, Moore, Holly, Gaisler-Salomon, Inna, Rayport, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599237/
https://ncbi.nlm.nih.gov/pubmed/28703706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27566
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