BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction

BET proteins are a group of epigenetic regulators controlling transcription through reading acetylated histone tails and recruiting transcription complexes. They are considered as potential therapeutic targets in many distinct diseases. A novel synthetic bromodomain and extraterminal domain (BET) in...

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Autores principales: Meng, S., Zhang, L., Tang, Y., Tu, Q., Zheng, L., Yu, L., Murray, D., Cheng, J., Kim, S.H., Zhou, X., Chen, J.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2014
Materias:
Research Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107547/
https://ncbi.nlm.nih.gov/pubmed/24799421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034514534261
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