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BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction
BET proteins are a group of epigenetic regulators controlling transcription through reading acetylated histone tails and recruiting transcription complexes. They are considered as potential therapeutic targets in many distinct diseases. A novel synthetic bromodomain and extraterminal domain (BET) in...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107547/ https://ncbi.nlm.nih.gov/pubmed/24799421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034514534261 |
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