A carregar...
Scalable syntheses of the BET bromodomain inhibitor JQ1
We have developed methods involving the use of alternate, safer reagents for the scalable syntheses of the potent BET bromodomain inhibitor JQ1. A one-pot three step method, involving the conversion of a benzodiazepine to a thioamde using Lawesson’s reagent, followed by amidrazone formation and inst...
Na minha lista:
| Publicado no: | Tetrahedron Lett |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4448696/ https://ncbi.nlm.nih.gov/pubmed/26034331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.02.062 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|