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Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation
Maturation of dendritic cells (DCs) is required to induce T-cell immunity while immature DCs can induce immune tolerance. Although the transcription factor STAT5 is suggested to participate in DC maturation, its role in this process remains unclear. Here, we investigated the effect of STAT5 inhibiti...
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| I publikationen: | J Immunol |
|---|---|
| Huvudupphovsmän: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369449/ https://ncbi.nlm.nih.gov/pubmed/25725100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401635 |
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