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Aminoacyl β-naphthylamides as substrates and modulators of AcrB multidrug efflux pump
Efflux pumps of the resistance-nodulation division superfamily, such as AcrB, make a major contribution to multidrug resistance in Gram-negative bacteria. Inhibitors of such pumps would improve the efficacy of antibiotics, and ameliorate the crisis in health care caused by the prevalence of multidru...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747751/ https://ncbi.nlm.nih.gov/pubmed/26787896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525143113 |
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