טוען...
Force sensing by the vascular protein von Willebrand factor is tuned by a strong intermonomer interaction
The large plasma glycoprotein von Willebrand factor (VWF) senses hydrodynamic forces in the bloodstream and responds to elevated forces with abrupt elongation, thereby increasing its adhesiveness to platelets and collagen. Remarkably, forces on VWF are elevated at sites of vascular injury, where VWF...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747740/ https://ncbi.nlm.nih.gov/pubmed/26787887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516214113 |
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