pH-Dependent Interactions in Dimers Govern the Mechanics and Structure of von Willebrand Factor

Von Willebrand factor (VWF) is a multimeric plasma glycoprotein that is activated for hemostasis by increased hydrodynamic forces at sites of vascular injury. Here, we present data from atomic force microscopy-based single-molecule force measurements, atomic force microscopy imaging, and small-angle...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Müller, Jochen P., Löf, Achim, Mielke, Salomé, Obser, Tobias, Bruetzel, Linda K., Vanderlinden, Willem, Lipfert, Jan, Schneppenheim, Reinhard, Benoit, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968480/
https://ncbi.nlm.nih.gov/pubmed/27463134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.06.022
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