Cetuximab enhanced the efficacy of chemotherapeutic agent in ABCB1/P-glycoprotein-overexpressing cancer cells

The overexpression of ATP-binding cassette (ABC) transporters is closely associated with the development of multidrug resistance (MDR) in certain types of cancer, which represents a formidable obstacle to the successful cancer chemotherapy. Here, we investigated that cetuximab, an EGFR monoclonal an...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Fang, Chen, Yifan, Huang, Lihua, Liu, Tao, Huang, Yue, Zhao, Jianming, Wang, Xiaokun, Yang, Ke, Ma, Shaolin, Huang, Liyan, Wah To, Kenneth Kin, Gu, Yong, Fu, Liwu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747373/
https://ncbi.nlm.nih.gov/pubmed/26506420
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