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Sensitization of ABCB1 Overexpressing Cells to Chemotherapeutic Agents by FG020326 via Binding to ABCB1 and Inhibiting Its Function
The effectiveness of chemotherapeutic treatment is usually limited by the overexpression of adenosine triphosphate binding cassette (ABC) transporters, which mediate multidrug resistance (MDR) by acting as efflux pumps to remove chemotherapeutic agents from MDR cancer cells. Thus, the inhibition of...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798597/ https://ncbi.nlm.nih.gov/pubmed/19410561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.04.023 |
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