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Sitravatinib Sensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs

The development of multidrug resistance (MDR) in cancer patients driven by the overexpression of ATP-binding cassette (ABC) transporter ABCB1 or ABCG2 in cancer cells presents one of the most daunting therapeutic complications for clinical scientists to resolve. Despite many novel therapeutic strate...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Wu, Chung-Pu, Hsiao, Sung-Han, Huang, Yang-Hui, Hung, Lang-Cheng, Yu, Yi-Jou, Chang, Yu-Tzu, Hung, Tai-Ho, Wu, Yu-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017071/
https://ncbi.nlm.nih.gov/pubmed/31941029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010195
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