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Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs

The overexpression of the ATP-binding cassette (ABC) transporter ABCG2 has been linked to clinical multidrug resistance in solid tumors and blood cancers, which remains a significant obstacle to successful cancer chemotherapy. For years, the potential modulatory effect of bioactive compounds derived...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Wu, Chung-Pu, Lusvarghi, Sabrina, Hsiao, Sung-Han, Liu, Te-Chun, Li, Yan-Qing, Huang, Yang-Hui, Hung, Tai-Ho, Ambudkar, Suresh. V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402219/
https://ncbi.nlm.nih.gov/pubmed/32347726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.9b01022
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