Erdafitinib Resensitizes ABCB1-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs

The development of multidrug resistance (MDR) in cancer patients, which is often associated with the overexpression of ABCB1 (MDR1, P-glycoprotein) in cancer cells, remains a significant problem in cancer chemotherapy. ABCB1 is one of the major adenosine triphosphate (ATP)-binding cassette (ABC) tra...

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Publicado en:Cancers (Basel)
Autores principales: Wu, Chung-Pu, Hung, Tai-Ho, Hsiao, Sung-Han, Huang, Yang-Hui, Hung, Lang-Cheng, Yu, Yi-Jou, Chang, Yu-Tzu, Wang, Shun-Ping, Wu, Yu-Shan
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352346/
https://ncbi.nlm.nih.gov/pubmed/32466597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061366
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