Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance

Sildenafil is a potent and selective inhibitor of the type 5 cGMP-specific phosphodiesterase that is used clinically to treat erectile dysfunction and pulmonary arterial hypertension. Here we report that sildenafil has differential effects on cell surface ABC transporters such as ABCB1, ABCC1 and AB...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shi, Zhi, Tiwari, Amit K, Shukla, Suneet, Robey, Robert W., Singh, Satyakam, Kim, In-Wha, Bates, Susan E., Peng, Xingxiang, Abraham, Ioana, Ambudkar, Suresh V., Talele, Tanaji T., Fu, Li-Wu, Chen, Zhe-Sheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078184/
https://ncbi.nlm.nih.gov/pubmed/21402712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3820
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