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Nobiletin enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cancer cells
Multidrug resistance (MDR) is the major obstacle to the successful chemotherapy treatment of many cancers. Here we found that nobiletin, a citrus methoxyflavone, significantly sensitized ABCB1 overexpressing cells A2780/T and A549/T to chemotherapeutic agents such as paclitaxel (a 433-fold reversal...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4686932/ https://ncbi.nlm.nih.gov/pubmed/26689156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18789 |
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