UMMS-4 enhanced sensitivity of chemotherapeutic agents to ABCB1-overexpressing cells via inhibiting function of ABCB1 transporter

Multidrug resistance (MDR) mediated by ATP-binding cassette (ABC) transporters through efflux of antineoplastic agents from cancer cells is a major obstacle to successful cancer chemotherapy. The inhibition of these ABC transporters is thus a logical approach to circumvent MDR. There has been intens...

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Autors principals: Qiao, Dongjuan, Tang, Shangjun, Aslam, Sana, Ahmad, Matloob, To, Kenneth Kin Wah, Wang, Fang, Huang, Zhencong, Cai, Jiye, Fu, Liwu
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960452/
https://ncbi.nlm.nih.gov/pubmed/24660104
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