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Human Frataxin Folds Via an Intermediate State. Role of the C-Terminal Region
The aim of this study is to investigate the folding reaction of human frataxin, whose deficiency causes the neurodegenerative disease Friedreich’s Ataxia (FRDA). The characterization of different conformational states would provide knowledge about how frataxin can be stabilized without altering its...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4746760/ https://ncbi.nlm.nih.gov/pubmed/26856628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20782 |
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