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Protein Stability and Dynamics Modulation: The Case of Human Frataxin
Frataxin (FXN) is an α/β protein that plays an essential role in iron homeostasis. Apparently, the function of human FXN (hFXN) depends on the cooperative formation of crucial interactions between helix α1, helix α2, and the C-terminal region (CTR) of the protein. In this work we quantitatively expl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458073/ https://ncbi.nlm.nih.gov/pubmed/23049850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045743 |
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