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The role of the N-terminal tail for the oligomerization, folding and stability of human frataxin()
The N-terminal stretch of human frataxin (hFXN) intermediate (residues 42–80) is not conserved throughout evolution and, under defined experimental conditions, behaves as a random-coil. Overexpression of hFXN56–210 in Escherichia coli yields a multimer, whereas the mature form of hFXN (hFXN81–210) i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741918/ https://ncbi.nlm.nih.gov/pubmed/23951553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.07.004 |
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