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Protein Stability and Dynamics Modulation: The Case of Human Frataxin

Frataxin (FXN) is an α/β protein that plays an essential role in iron homeostasis. Apparently, the function of human FXN (hFXN) depends on the cooperative formation of crucial interactions between helix α1, helix α2, and the C-terminal region (CTR) of the protein. In this work we quantitatively expl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Roman, Ernesto A., Faraj, Santiago E., Gallo, Mariana, Salvay, Andres G., Ferreiro, Diego U., Santos, Javier
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458073/
https://ncbi.nlm.nih.gov/pubmed/23049850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045743
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