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Folding of apocytochrome c induced by the interaction with negatively charged lipid micelles proceeds via a collapsed intermediate state.

Unfolded apocytochrome c acquires an alpha-helical conformation upon interaction with lipid. Folding kinetic results below and above the lipid's CMC, together with energy transfer measurements of lipid bound states, and salt-induced compact states in solution, show that the folding transition o...

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Autors principals: Rankin, S. E., Watts, A., Roder, H., Pinheiro, T. J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144269/
https://ncbi.nlm.nih.gov/pubmed/10048331
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